Tuesday 07 April 2020

M30: Getting to Zero: PrEP, treatment for all and differentiated care to reduce incidence and mortality


This training workshop describes the major role that pre-exposure prophylaxis (PrEP) to prevent HIV acquisition and treatment as prevention have in reducing HIV incidence and mortality, and bringing the epidemic under control. As of September 2015, WHO recommends that people at substantial risk of HIV infection should be offered PrEP as an additional prevention choice, as part of comprehensive prevention strategies. Demonstration projects have shown its potential value in diverse settings, as well as strong demand and adherence among people at high risk of HIV infection, including HIV-negative partners within mixed status couples, men who have sex with men, young women and female sex workers.

Lectures will outline steps that are necessary for the implementation of PreP programmes, as recommended in the WHO Implementation Tool for Prep, as well as how to address factors that limit the PrEP availability and increase the access to PreP.

Further, the course will focus on the HIV Treatment as Prevention (TasP) strategy. Despite evidence supporting huge benefits of TasP and “test and treat”, their success at the population level requires overcoming a set of complex and population-specific implementation challenges. Lectures and case studies will describe the major issues that influence the success of “test and treat”, the key cornerstone of UNAIDS’ 90-90-90 targets to end AIDS as a major public health threat by 2030. Among those are low linkage to care among HIV diagnosed, late ART initiation and less than adequate retention on ART. Presentations will provide a detailed overview of innovative interventions that can be used to improve linkage and retention across the continuum of HIV prevention and treatment services.

Finally, participants will learn about various differentiated ART delivery models and monitoring and evaluation approaches. Differentiated care is a client-centred approach that simplifies and adapts HIV services across the cascade to reflect the preferences and expectations of various groups of people living with HIV while reducing unnecessary burdens on the health system. 

Differentiated care is promoted by the latest WHO consolidated ARV guidelines, and major donors, including PEPFAR and the Global Fund, and has been adopted as policy in a number of countries.

The learning objectives are to:

  • Provide an overview of PreP implementation and monitoring and evaluation strategies
  • Present examples of successful PreP implementation programmes
  • Understand and discuss barriers to PreP implementation and how these can be overcome
  • Present innovative and evidence-based interventions that can be used to optimize “test and treat” strategies and improve linkage to HIV care and ART initiation, and retention along the HIV care continuum 
  • Present an up-to-date overview of methods used to measure HIV incidence and mortality
  • Practice development of protocols for implementation and evaluation of PreP programmes, or a protocol for implementation of a differentiated ART delivery model

Teaching Methods

The course consists of lectures, exercises and case studies.

Participants can choose among the following options for group work/exercise:

  • protocol for a PreP implementation project
  • protocol for monitoring and evaluation of a PreP intervention project/ programme
  • protocol/ operational plan for implementation of a differentiated HIV care model

Draft protocols will be presented by participants during the final day of the workshop.

Target audience:

Professionals who work on HIV programme implementation, epidemiologists, social scientists, public health professionals.

Course lecturers and facilitators:

  • Professor George W. Rutherford, MD, Global Health Sciences, University of California, San Francisco, USA
  • Associate professor Ivana Božičević, MD, MSc, DrPH, WHO Collaborating Centre for HIV Strategic Information, School of Medicine, University of Zagreb
  • Zoran Dominković, WHO Collaborating Centre for HIV Strategic Information, School of Medicine, University of Zagreb
  • WHO: to be confirmed

Course organizer:

Lucija Šikić, WHO Collaborating Centre for HIV Strategic Information, University of Zagreb School of Medicine

Duration and site: 

The course takes place in five days, 25 – 29 June 2018 at the WHO Collaborating Centre for HIV Surveillance, Zagreb, Croatia.

To apply for the course please apply on-line at http://www.whohub-zagreb.org/apply/registration or contact Ms Lucija Šikić at: lsikic@snz.hrtraining@snz.hr.

The course will be held at:

WHO Collaborating Centre for HIV Surveillance
Andrija Stampar School of Public Health
University of Zagreb School of Medicine
Rockefellerova 4
10 000 Zagreb, Croatia
Phone: + 385 1 45 90 142/ 45 90 100


The course fee is 1000 USD and includes training materials and lunch and coffee/tea breaks during the course.



Download the Programme


Programme - PrEP, TasP, differentiated ART delivery.docx

Created by hrvo.je.